BDBM438472 US10618903, Example 100

SMILES C[C@H](Nc1cc(ncc1C(=O)NC[C@@H](F)C(C)(C)O)-c1cnn2cc(cnc12)C#N)C(C)(C)O

InChI Key InChIKey=YHEGYVOJPMNMHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 438472   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM438472(US10618903, Example 100)
Affinity DataIC50: 94nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent