BDBM438653 US10618903, Example 220

SMILES CC(C)Nc1cc(ncc1C(=O)N[C@H]1CC[C@@H](CC1)NC(C)=O)-c1cnc2cc(cnn12)C#N

InChI Key InChIKey=DZYLHICSUPXOGD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 438653   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM438653(US10618903, Example 220)
Affinity DataIC50: 16nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent