BDBM439233 US10604514, Compound 121

SMILES Cc1nnc(s1)-c1ccc2cnc(NC(=O)N3CCC(CC3)NC(CF)CF)cc2c1

InChI Key InChIKey=XRJQWINHBKCFAS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439233   

LigandPNGBDBM439233(US10604514, Compound 121)
Affinity DataEC50:  35nMAssay Description:Briefly, recombinant DYRK1A kinase, ATP and Ser/Thr peptide 18 were prepared in 1 Kinase buffer to final concentrations of 0.19 μg/mL, 30 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2020
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Samumed

US Patent
LigandPNGBDBM439233(US10604514, Compound 121)
Affinity DataEC50:  82nMAssay Description:Briefly, recombinant GSK3β kinase, ATP and Ser/Thr peptide 09 are prepared in 1 Kinase buffer to final concentrations of 0.04 μg/mL, 46 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2020
Entry Details
US Patent