BDBM439707 US10633389, Example 15-1a::US20230279020, Example 15-1a

SMILES Cc1noc(C)c1-c1cc(NC2CCOCC2)nc(n1)-c1cccc(OC[C@@H](O)CN)c1

InChI Key InChIKey=VTPKOXMRCLHJJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 439707   

TargetHistone-arginine methyltransferase CARM1(Human)
Epizyme

US Patent
LigandPNGBDBM439707(US10633389, Example 15-1a | US20230279020, Example...)
Affinity DataIC50: 100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween 20, prepared on the day of use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetHistone-arginine methyltransferase CARM1(Human)
Epizyme

US Patent
LigandPNGBDBM439707(US10633389, Example 15-1a | US20230279020, Example...)
Affinity DataIC50: 100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween 20, prepared on the day of use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
US Patent