BDBM442066 US10647713, Compound I-9::US11396508, Compound I-9
SMILES COc1c(Nc2cc(NC(=O)C3CC3)nc3[nH]c(nc23)C2CC2)cccc1-c1ncn(C)n1
InChI Key InChIKey=OACJHQSURCAFDD-UHFFFAOYSA-N
Data 2 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 442066
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshmi
US Patent
Nimbus Lakshmi
US Patent
Affinity DataKd: >10nMAssay Description:The binding reaction was assembled by combining 16 μl of DNA-tagged kinase extract, 3.8 μl liganded affinity beads, and 0.18 μl test c...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshmi
US Patent
Nimbus Lakshmi
US Patent
Affinity DataKd: >10nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair