BDBM442745 Ethyl 7-chloro-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate::US10647727, Example 3

SMILES C[C@H](Nc1nc(Cl)nc2n(C)ncc12)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=ZYAUUUUKFRDVKN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 442745   

TargetPhosphodiesterase(Rhesus macaque)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM442745(US10647727, Example 3 | Ethyl 7-chloro-5-methylpyr...)
Affinity DataKi:  4.79E+3nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
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Date in BDB:
1/25/2021
Entry Details
US Patent