BDBM443047 2-((3-(benzyloxy)phenyl)amino)-N- hydroxy-1H-benzo[d]imidazole-6- carboxamide::US10654814, Example 132

SMILES ONC(=O)c1ccc2nc(Nc3cccc(OCc4ccccc4)c3)[nH]c2c1

InChI Key InChIKey=YHNAHGDELYOYSK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 443047   

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM443047(US10654814, Example 132 | 2-((3-(benzyloxy)phenyl)...)
Affinity DataIC50: 17nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Kancera

US Patent
LigandPNGBDBM443047(US10654814, Example 132 | 2-((3-(benzyloxy)phenyl)...)
Affinity DataIC50: 17nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Kancera

US Patent
LigandPNGBDBM443047(US10654814, Example 132 | 2-((3-(benzyloxy)phenyl)...)
Affinity DataIC50: 240nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Kancera

US Patent
LigandPNGBDBM443047(US10654814, Example 132 | 2-((3-(benzyloxy)phenyl)...)
Affinity DataIC50: 370nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Kancera

US Patent
LigandPNGBDBM443047(US10654814, Example 132 | 2-((3-(benzyloxy)phenyl)...)
Affinity DataIC50: 1.20E+3nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Kancera

US Patent
LigandPNGBDBM443047(US10654814, Example 132 | 2-((3-(benzyloxy)phenyl)...)
Affinity DataIC50: 2.40E+4nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2021
Entry Details
US Patent