BDBM443273 1-Cyano-N,N-dimethyl-2′-oxo-1′,4′-dihydro-2′H-spiro[pyrrolidine-3,3′-quinoline]-7′-carboxamide::US10654853, Example 46::US11236092, Example 46

SMILES CN(C)C(=O)c1ccc2CC3(CCN(C3)C#N)C(=O)Nc2c1

InChI Key InChIKey=VQNIFRUAGGWIJA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443273   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443273BDBM443273(US10654853, Example 46 | 1-Cyano-N,N-dimethyl-2...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443273BDBM443273(US10654853, Example 46 | 1-Cyano-N,N-dimethyl-2...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent