BDBM443303 (8R)-8-Methyl-7,10-dioxo-2,6,9-triazaspiro[4.5]decane-2-carbonitrile::US10654853, Example 76::US11236092, Example 76

SMILES C[C@H]1NC(=O)C2(CCN(C2)C#N)NC1=O

InChI Key InChIKey=XNJLFQMZCFESGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443303   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443303BDBM443303(US10654853, Example 76 | (8R)-8-Methyl-7,10-dioxo-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443303BDBM443303(US10654853, Example 76 | (8R)-8-Methyl-7,10-dioxo-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
US Patent