BDBM443308 8-Benzyl-6-oxo-2,7-diazaspiro[4.4]nonane-2-carbonitrile::US10654853, Example 81::US11236092, Example 81

SMILES O=C1NC(Cc2ccccc2)CC11CCN(C1)C#N

InChI Key InChIKey=PPDJKDJCOKVMIU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443308   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443308BDBM443308(US10654853, Example 81 | 8-Benzyl-6-oxo-2,7-diazas...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443308BDBM443308(US10654853, Example 81 | 8-Benzyl-6-oxo-2,7-diazas...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent