BDBM44464 2-(2-chloro-N-mesyl-anilino)-N-(3-chlorophenyl)acetamide::2-(2-chloro-N-methylsulfonylanilino)-N-(3-chlorophenyl)acetamide::CHEMBL1451902::MLS000530551::N-(3-chlorophenyl)-2-[(2-chlorophenyl)-methylsulfonyl-amino]ethanamide::N~2~-(2-chlorophenyl)-N~1~-(3-chlorophenyl)-N~2~-(methylsulfonyl)glycinamide::SMR000135531::cid_1364364

SMILES CS(=O)(=O)N(CC(=O)Nc1cccc(Cl)c1)c1ccccc1Cl

InChI Key InChIKey=UUYQFOSWDVZCAB-UHFFFAOYSA-N

Data  1 KI  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 44464   

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM44464(N~2~-(2-chlorophenyl)-N~1~-(3-chlorophenyl)-N~2~-(...)
Affinity DataEC50:  77.6nMAssay Description:Ago-positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells by fluorescence-based calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM44464(N~2~-(2-chlorophenyl)-N~1~-(3-chlorophenyl)-N~2~-(...)
Affinity DataEC50:  80nMAssay Description:Ago-positive allosteric modulation of rat mGlu5 receptor expressed in HEK293 cells by fluorescence-based calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM44464(N~2~-(2-chlorophenyl)-N~1~-(3-chlorophenyl)-N~2~-(...)
Affinity DataEC50:  776nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells by fluorescence-based calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM44464(N~2~-(2-chlorophenyl)-N~1~-(3-chlorophenyl)-N~2~-(...)
Affinity DataEC50:  780nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells by fluorescence-based calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM44464(N~2~-(2-chlorophenyl)-N~1~-(3-chlorophenyl)-N~2~-(...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-methoxyPEPy from rat mGlu5 receptor expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEphrin type-A receptor 4(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM44464(N~2~-(2-chlorophenyl)-N~1~-(3-chlorophenyl)-N~2~-(...)
Affinity DataIC50: 5.00E+4nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2011
Entry Details
PCBioAssay
TargetEphrin type-A receptor 4(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM44464(N~2~-(2-chlorophenyl)-N~1~-(3-chlorophenyl)-N~2~-(...)
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2011
Entry Details
PCBioAssay