BDBM445079 (S)-2-(5-(5-(trifluoromethyl)- 1H-pyrazol-4-yl)indoline- 1-carbonyl)pyrrolidine-1- carbonitrile::US10669234, Example 18::US11319287, Example 18

SMILES N#CN1CCC[C@H]1C(=O)N1CCc2cc(-c3cn[nH]c3C(F)(F)F)ccc21

InChI Key InChIKey=FYIRZBLRACCKNX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445079   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445079BDBM445079(US10669234, Example 18 | (S)-2-(5-(5-(trifluoromet...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445079BDBM445079(US10669234, Example 18 | (S)-2-(5-(5-(trifluoromet...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent