BDBM445093 (S)-2-(4-phenylisoindoline- 2-carbonyl)pyrrolidine- 1-carbonitrile::US10669234, Example 32::US11319287, Example 32

SMILES O=C([C@@H]1CCCN1C#N)N1Cc2cccc(c2C1)-c1ccccc1

InChI Key InChIKey=GHESLAQUATUPKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445093   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445093BDBM445093(US10669234, Example 32 | (S)-2-(4-phenylisoindolin...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445093BDBM445093(US10669234, Example 32 | (S)-2-(4-phenylisoindolin...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent