BDBM445097 (S)-2-(4-(pyrimidin-4-yl)- indoline-1-carbonyl)pyrrolidine- 1-carbonitrile::US10669234, Example 36::US11319287, Example 36

SMILES O=C([C@@H]1CCCN1C#N)N1CCc2c1cccc2-c1ccncn1

InChI Key InChIKey=SOGGLSWYHHABAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445097   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445097BDBM445097(US10669234, Example 36 | (S)-2-(4-(pyrimidin-4-yl)...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445097BDBM445097(US10669234, Example 36 | (S)-2-(4-(pyrimidin-4-yl)...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent