BDBM445106 (S)-2-(5-phenyl-1,2,3,4- tetrahydroquinoline-1- carbonyl)pyrrolidine-1- carbonitrile::US10669234, Example 45::US11319287, Example 45

SMILES O=C([C@@H]1CCCN1C#N)N1CCCc2c1cccc2-c1ccccc1

InChI Key InChIKey=HBUQOCHFSXXTAY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445106   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445106BDBM445106(US10669234, Example 45 | (S)-2-(5-phenyl-1,2,3,4- ...)
Affinity DataIC50: 5.50E+4nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445106BDBM445106(US10669234, Example 45 | (S)-2-(5-phenyl-1,2,3,4- ...)
Affinity DataIC50: 5.50E+4nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent