BDBM445128 (S)-N-(3-(4-chlorophenyl)- isoxazol-5-yl)-1-cyano-N- methylpyrrolidine- 2-carboxamide::US10669234, Example 67::US11319287, Example 67

SMILES CN(C(=O)[C@@H]1CCCN1C#N)c1cc(no1)-c1ccc(Cl)cc1

InChI Key InChIKey=UGRRMXPVIFJDNJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 445128   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445128BDBM445128(US10669234, Example 67 | (S)-N-(3-(4-chlorophenyl)...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445128BDBM445128(US10669234, Example 67 | (S)-N-(3-(4-chlorophenyl)...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445128BDBM445128(US10669234, Example 67 | (S)-N-(3-(4-chlorophenyl)...)
Affinity DataIC50: 5.50E+4nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445128BDBM445128(US10669234, Example 67 | (S)-N-(3-(4-chlorophenyl)...)
Affinity DataIC50: 5.50E+4nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent