BDBM445797 US10669240, Compound 93

SMILES CC(C)CN1CCC(CC1)NC(=O)c1n[nH]c2ccc(cc12)-c1cccc(F)c1F

InChI Key InChIKey=IPBVMBFTMMTZPK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445797   

TargetProto-oncogene Wnt-1(Human)
Samumed

US Patent
LigandPNGBDBM445797(US10669240, Compound 93)
Affinity DataIC50: 526nMAssay Description:Reporter cell lines were generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM445797(US10669240, Compound 93)
Affinity DataEC50:  73nMAssay Description:SH-SY5Y cells are cultured in DMEM/F-12 medium supplemented with 15% FBS, Non-essential Amino Acid and Penicillin/Streptamycin. Two days before treat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent