BDBM446004 US10669246, Example 55::US10968188, Example 55
SMILES COc1ccncc1-c1ccc2nc(NC(=O)[C@@H]3C[C@@H]3F)sc2c1
InChI Key InChIKey=RYDXEOCUWPNWBT-PWSUYJOCSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 446004
Affinity DataIC50: 5.90nMAssay Description:ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), bovine serum albumin (BSA), ethylene glycol-bis(β-aminoethyl ether)-N,...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Inhibition of recombinant human His-tagged c-Abl kinase assessed as luminescence incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated w...More data for this Ligand-Target Pair