BDBM448175 (R)-8-isopropyl-6- methyl-2-neopentyl-5-oxa- 2,8-diazaspiro[3.5]nonan- 7-one::US10689398, Example 77

SMILES CC(C)N1CC2(CN(CC(C)(C)C)C2)O[C@H](C)C1=O

InChI Key InChIKey=XKWNQRFKBYAEST-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448175   

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM448175((R)-8-isopropyl-6- methyl-2-neopentyl-5-oxa- 2,8-d...)
Affinity DataKi: >500nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent