BDBM448208 US10689401, EX 12::US11008338, Example 12
SMILES COc1ccc(F)c(c1)[C@]12CO[C@H](C[C@H]1S(=O)(=O)C(C)(C)C(=N)N2)c1ccc(F)cc1
InChI Key InChIKey=QHXIKGDWSQXRCG-WOIUINJBSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 448208
Affinity DataKi: 96.3nMAssay Description:BACE-2: Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY...More data for this Ligand-Target Pair
Affinity DataKi: 96.3nMAssay Description:BACE2: Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7...More data for this Ligand-Target Pair
Affinity DataKi: 184nMAssay Description:BACE1: A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This a...More data for this Ligand-Target Pair
Affinity DataKi: 184nMAssay Description:BACE1: A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This a...More data for this Ligand-Target Pair