BDBM448549 US10696655, Example 22::US11168070, Example 22

SMILES Cn1cc(cn1)-c1cc2CCCN(c3ccc4n(C)c(=O)sc4c3)c2cc1C(F)F

InChI Key InChIKey=SCGRYUJYTJLDNX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448549   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448549BDBM448549(US10696655, Example 22 | US11168070, Example 22)
Affinity DataIC50: 1.69E+3nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448549BDBM448549(US10696655, Example 22 | US11168070, Example 22)
Affinity DataIC50: 1.69E+3nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent