BDBM448629 1,3-dimethyl-5-(4-methyl-6-(1-methyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)-1H-benzo[d]imidazol-2(3H)-one::US10696655, Example 95::US11168070, Example 95

SMILES CN1CCN(c2ccc3n(C)c(=O)n(C)c3c2)c2cc(c(cc12)-c1cnn(C)c1)C(F)(F)F

InChI Key InChIKey=NNHUZYVBCCQHDP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448629   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448629BDBM448629(US10696655, Example 95 | 1,3-dimethyl-5-(4-methyl-...)
Affinity DataIC50: 30nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448629BDBM448629(US10696655, Example 95 | 1,3-dimethyl-5-(4-methyl-...)
Affinity DataIC50: 30nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent