BDBM448644 9-isopropyl-N-methyl-7-(o-tolyl)-2,3-dihydrobenzo[f][1,4]oxazepine-4(5H)-carboxamide::US10696655, Example 110::US11168070, Example 110

SMILES CNC(=O)N1CCOc2c(C1)cc(cc2C(C)C)-c1ccccc1C

InChI Key InChIKey=OCBQGIWJLCJCCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448644   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448644BDBM448644(US10696655, Example 110 | 9-isopropyl-N-methyl-7-(...)
Affinity DataIC50: 201nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448644BDBM448644(US10696655, Example 110 | 9-isopropyl-N-methyl-7-(...)
Affinity DataIC50: 201nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent