BDBM449975 US10703755, Example 93

SMILES CCOc1nc(N)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4CCN(C)C(=O)C4)cc3)c2n1

InChI Key InChIKey=OKTSJCHTEGGKIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 449975   

TargetToll-like receptor 7(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM449975(US10703755, Example 93)
Affinity DataIC50: 290nMAssay Description:As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter HEK293 cell), which is human embr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
Go to US Patent