BDBM450198 9-({1-[(3S)-1-Azabicyclo[2.2.2]oct-3-ylmethyl]-1H-pyrazol-4-yl}methyl)-2-ethoxy-8-(3-fluoropyridin-3-yl)-6-methyl-9H-purine::US10703755, Example 398

SMILES CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3cnn(C[C@@H]4CN5CC[C@H]4CC5)c3)c2n1

InChI Key InChIKey=NKDZCISFCIMWIN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450198   

TargetToll-like receptor 7(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM450198(9-({1-[(3S)-1-Azabicyclo[2.2.2]oct-3-ylmethyl]-1H-...)
Affinity DataIC50: 21nMAssay Description:As human TLR7 expressing cell line, HEK293 cell line was bought from IMGENEX Corporation (TLR7/NF-ηB/SEAPorter HEK293 cell), which is human embr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent