BDBM450500 Methyl 2-[4-[3-[2-[(3,4-dichlorophenyl)methylamino]-2-oxoethyl]-4-oxoquinazolin-6-yl]piperazin-1-yl]acetate::US10676446, Example 93
SMILES COC(=O)CN1CCN(CC1)c1ccc2ncn(CC(=O)NCc3ccc(Cl)c(Cl)c3)c(=O)c2c1
InChI Key InChIKey=KHJKSUFHXLGNED-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 450500
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 29nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair