BDBM450500 Methyl 2-[4-[3-[2-[(3,4-dichlorophenyl)methylamino]-2-oxoethyl]-4-oxoquinazolin-6-yl]piperazin-1-yl]acetate::US10676446, Example 93

SMILES COC(=O)CN1CCN(CC1)c1ccc2ncn(CC(=O)NCc3ccc(Cl)c(Cl)c3)c(=O)c2c1

InChI Key InChIKey=KHJKSUFHXLGNED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450500   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM450500(Methyl 2-[4-[3-[2-[(3,4-dichlorophenyl)methylamino...)
Affinity DataIC50:  29nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent