BDBM450645 1-(2-methoxyethyl)-2-{[4-(2-phenyl-1,3- benzodioxol-4-yl)piperazin-1-yl]methyl}- 1H-benzimidazole-6-carboxylic acid, ENT-X1, trifluoroacetate salt, [from P5]::US10676465, Example 22::US10676465, Example 23

SMILES COCCn1c(CN2CCN(CC2)c2cccc3OC(Oc23)c2ccccc2)nc2ccc(cc12)C(O)=O

InChI Key InChIKey=SVBZCXLXGVIDCB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450645   

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM450645(US10676465, Example 22 | 1-(2-methoxyethyl)-2-{[4-...)
Affinity DataEC50:  680nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

TargetGlucagon-like peptide 1 receptor(Human)
Pfizer

US Patent
LigandPNGBDBM450645(US10676465, Example 22 | 1-(2-methoxyethyl)-2-{[4-...)
Affinity DataEC50: >2.00E+4nMAssay Description:GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent