BDBM450996 N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-::US10676479, Example 27

SMILES CS(=O)(=O)c1cccc(c1)-c1cnc(NCc2c3CCOc3ccc2F)n2cncc12

InChI Key InChIKey=QWQHIRBPLPABLE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 450996   

LigandChemical structure of BindingDB Monomer ID 450996BDBM450996(US10676479, Example 27 | N-((5-fluoro-2,3-dihydrob...)
Affinity DataIC50: 23.5nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 450996BDBM450996(US10676479, Example 27 | N-((5-fluoro-2,3-dihydrob...)
Affinity DataIC50: 24.1nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 450996BDBM450996(US10676479, Example 27 | N-((5-fluoro-2,3-dihydrob...)
Affinity DataIC50: 43nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent