BDBM451001 5-(5-(((5-fluoro-2,3-dihydrobenzofuran-4-::US10676479, Example 31

SMILES Fc1ccc2OCCc2c1CNc1ncc(-c2ccc(nc2)C#N)c2cncn12

InChI Key InChIKey=ZXNDZMFCNRXLTK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 451001   

LigandPNGBDBM451001(US10676479, Example 31 | 5-(5-(((5-fluoro-2,3-dihy...)
Affinity DataIC50: 14.4nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

LigandPNGBDBM451001(US10676479, Example 31 | 5-(5-(((5-fluoro-2,3-dihy...)
Affinity DataIC50: 20.9nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

LigandPNGBDBM451001(US10676479, Example 31 | 5-(5-(((5-fluoro-2,3-dihy...)
Affinity DataIC50: 39.9nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent