BDBM451018 N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-::US10676479, Example 48

SMILES Cc1cc(ccc1S(C)(=O)=O)-c1cnc(NCc2c3CCOc3ccc2F)n2cncc12

InChI Key InChIKey=CGILJVPHUVXAHB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 451018   

LigandChemical structure of BindingDB Monomer ID 451018BDBM451018(US10676479, Example 48 | N-((5-fluoro-2,3-dihydrob...)
Affinity DataIC50: 10.5nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 451018BDBM451018(US10676479, Example 48 | N-((5-fluoro-2,3-dihydrob...)
Affinity DataIC50: 16.4nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 451018BDBM451018(US10676479, Example 48 | N-((5-fluoro-2,3-dihydrob...)
Affinity DataIC50: 34.1nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent