BDBM451019 2-(4-(5-(((5-fluoro-2,3-dihydrobenzofuran-4-::US10676479, Example 49

SMILES Cc1nn(CCO)c(C)c1-c1cnc(NCc2c(F)ccc3c2CCO3)n2cncc12

InChI Key InChIKey=JAFSAJQTBBSUPY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 451019   

LigandChemical structure of BindingDB Monomer ID 451019BDBM451019(US10676479, Example 49 | 2-(4-(5-(((5-fluoro-2,3-d...)
Affinity DataIC50: 7.90nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 451019BDBM451019(US10676479, Example 49 | 2-(4-(5-(((5-fluoro-2,3-d...)
Affinity DataIC50: 13.5nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 451019BDBM451019(US10676479, Example 49 | 2-(4-(5-(((5-fluoro-2,3-d...)
Affinity DataIC50: 20.4nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent