BDBM451067 US10676479, Example 97::ethyl 5-((2,4-difluoro-5-methoxybenzyl)amino)-8-

SMILES CCOC(=O)c1ncn2c(NCc3cc(OC)c(F)cc3F)ncc(-c3ccc(cc3)S(=O)(=O)N(C)C)c12

InChI Key InChIKey=CSEFBXLXZJKRMF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 451067   

LigandPNGBDBM451067(US10676479, Example 97 | ethyl 5-((2,4-difluoro-5-...)
Affinity DataIC50: 16.7nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
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LigandPNGBDBM451067(US10676479, Example 97 | ethyl 5-((2,4-difluoro-5-...)
Affinity DataIC50: 19.6nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
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LigandPNGBDBM451067(US10676479, Example 97 | ethyl 5-((2,4-difluoro-5-...)
Affinity DataIC50: 200nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent