BDBM451315 US10709709, Example 142

SMILES Cc1ncnc2n(ccc12)[C@@H]1C[C@H](Oc2cccc3CC[C@@H](N)c23)[C@@H](O)[C@H]1O

InChI Key InChIKey=FXDWWXDSCGKELM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 451315   

TargetProtein arginine N-methyltransferase 5(Human)
Pfizer

US Patent
LigandPNGBDBM451315(US10709709, Example 142)
Affinity DataIC50: 11nMAssay Description:Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent