BDBM451596 US10710967, Example 196

SMILES CC(C)C(=O)NCc1ccc(Cl)c(c1)-c1nc(cc(=O)[nH]1)-c1ccc(OCC2(C)COC2)nc1

InChI Key InChIKey=VNUWSOQJSMOTCE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 451596   

TargetProstaglandin E synthase(Human)
Aska Pharmaceutical

US Patent
LigandPNGBDBM451596(US10710967, Example 196)
Affinity DataIC50: 8.30nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent