BDBM451802 US10710980, Example 34::US10947218, Example 34
SMILES Nc1ncc(cc1C(=O)NC12CCC(O)(CC1)CC2)-c1ccc(cc1)[C@@]12C[C@@H]1CN(C2)C1CCOCC1
InChI Key InChIKey=KPRPFTOLWQQUAV-OCVAFRRMSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 451802
Affinity DataIC50: 18nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:In the applied method, this separation takes place inside a chip that contains a complex capillary system for simultaneous analysis of 12 samples (“1...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:A kinase selectivity panel which measures autophosphorylation using the ADP-Glo Kinase Assay (Promega, V9101) was set-up for wild-type ALK2 (aa172-49...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for wild-type ALK2 (aa172-499), ALK2 FOP mutant (aa172-499 R20...More data for this Ligand-Target Pair