BDBM453804 US10730863, Example 132

SMILES OC(=O)c1ccnc(c1)C#CC12CCC(CC1)(CC2)OCc1c(onc1-c1c(Cl)cccc1Cl)C1CC1

InChI Key InChIKey=NSSYCGXGDFDAML-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453804   

TargetBile acid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM453804(US10730863, Example 132)
Affinity DataEC50:  3.50E+3nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent