BDBM454956 US10730870, Example 124::US11512083, Example 124

SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CNC(=O)OC(C)(C)C)C(C)(C)C)cc1

InChI Key InChIKey=VTKNFMYABFTAQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 454956   

TargetVHL complex(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 454956BDBM454956(US10730870, Example 124 | US11512083, Example 124)
Affinity DataIC50: 1.11E+3nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

Targetvon Hippel-Lindau disease tumor suppressor(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 454956BDBM454956(US10730870, Example 124 | US11512083, Example 124)
Affinity DataIC50: 1.11E+3nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent