BDBM455181 US10730874, Compound I-199

SMILES CC(c1cn2cc(cc(C3CCC(=O)O3)c2n1)C1CC1)n1cc(nn1)C(=O)NCc1ncn2ccc(Cl)c(F)c12

InChI Key InChIKey=OCIUAWLYQAJILI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455181   

TargetPlasma kallikrein(Human)
Shire Human Genetic Therapies

US Patent
LigandPNGBDBM455181(US10730874, Compound I-199)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent