BDBM455304 US10730874, Compound TABLE II.9::US11352356, Table II.9

SMILES O=C(NCc1ncn2ccc(cc12)C1CC1)c1cnn(Cc2cn3cc(ccc3n2)C2CC2)c1

InChI Key InChIKey=BRSPMWXQBHDJIL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 455304   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM455304(US10730874, Compound TABLE II.9 | US11352356, Tabl...)
Affinity DataEC50:  1.05E+3nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM455304(US10730874, Compound TABLE II.9 | US11352356, Tabl...)
Affinity DataEC50:  1.05E+3nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent