BDBM456066 US10723723, Example 15-I::US10723723, Example 15-II

SMILES Cc1c2COC(=O)c2ccc1C(CO)NCCc1cccc(c1)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=GVTYFNJDZKGCIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 456066   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM456066(US10723723, Example 15-I | US10723723, Example 15-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM456066(US10723723, Example 15-I | US10723723, Example 15-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent