BDBM456121 US10723723, Example 31-I::US10723723, Example 31-II

SMILES CN(CC(O)c1ccc2C(=O)OCc2c1C)Cc1ccc(cc1)-c1cc(C)c(cn1)C#N

InChI Key InChIKey=GTBYTVJPSZSQQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 456121   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM456121(US10723723, Example 31-I | US10723723, Example 31-...)
Affinity DataIC50: 40nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM456121(US10723723, Example 31-I | US10723723, Example 31-...)
Affinity DataIC50: 370nMAssay Description:Solutions and reagents: Thallium flux assay was performed using FluxOR kit (F10017, Life Technologies). Loading buffer, assay buffer and stimulus buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent