BDBM456473 US10723742, Example 199::US11510915, Example 199

SMILES CC(C)(O)Cn1ncc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)C1CC2(CNC2)CN1

InChI Key InChIKey=CIZJIGSARHLUQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 456473   

TargetLysine-specific histone demethylase 1A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM456473(US10723742, Example 199 | US11510915, Example 199)
Affinity DataIC50: 1nMAssay Description:The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2021
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM456473(US10723742, Example 199 | US11510915, Example 199)
Affinity DataIC50: 1nMAssay Description:The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent