BDBM457050 US10738015, Example SC-15

SMILES CN(C)C1(CC2(C1)CN(C(=O)N2CC1CC1)c1cnc(cc1C)C#N)c1cccc(F)c1

InChI Key InChIKey=FVRLJLMVFUHOTB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457050   

TargetNociceptin receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM457050(US10738015, Example SC-15)
Affinity DataKi:  13nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl, 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
GrÜNenthal

US Patent
LigandPNGBDBM457050(US10738015, Example SC-15)
Affinity DataKi:  1.33E+3nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent