BDBM458741 4-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinazolin-7-yloxy)-1-(2-oxa-7-azaspiro[3.5]nonanyl)butan-1-one::US10758539, Compound 9

SMILES COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCC(=O)C1OCC11CCNCC1

InChI Key

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 458741   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kala Pharmaceuticals

US Patent
LigandPNGBDBM458741(4-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-6-methox...)
Affinity DataKd:  730nMAssay Description:A competition binding assay was used to measure the ability of a compound to compete for binding of an immobilized adenosine triphosphosphate (ATP) s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent