BDBM465470 US10793568, Compound I-121

SMILES OC(=O)c1ccc(N2C[C@@H]3C[C@H]2C[C@H]3OCc2c(onc2-c2ccccc2C(F)(F)F)C2CC2)c(F)c1

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465470   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM465470(US10793568, Compound I-121)
Affinity DataEC50:  3.16nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent