BDBM465549 US10793568, Compound I-199

SMILES Fc1cc(ccc1N1C[C@@H]2C[C@H]1C[C@H]2OC(=O)c1c(noc1C1(F)CC1)-c1c(Cl)cccc1Cl)C(=O)NS(=O)(=O)C1CC1

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465549   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM465549(US10793568, Compound I-199)
Affinity DataEC50:  39.8nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent