BDBM465618 US10793568, Compound I-269

SMILES Cc1cccc(Cl)c1-c1noc(C2CC2)c1CO[C@@H]1C[C@@H]2C[C@H]1CN2c1nc2c(C)cc(cc2s1)C(O)=O

InChI Key InChIKey=UBDBTIZMOXBWLI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465618   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM465618(US10793568, Compound I-269)
Affinity DataEC50:  3.16nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent