BDBM4683 4-Anilinoquinazoline 30::N-(4-bromo-2-fluorophenyl)-6-methoxy-7-{[(3R)-1-methylpiperidin-3-yl]methoxy}quinazolin-4-amine
SMILES COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OC[C@@H]1CCCN(C)C1
InChI Key InChIKey=JFGLOXKNWPNMQT-CQSZACIVSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 4683
Affinity DataIC50: 500nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit EGF-R RTK activity. The compounds were incubated with enzyme 20 min at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit FGFR-1 TK activity. The compounds were incubated with enzyme 20 min at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair