BDBM468495 US10806785, Example 133::trans-4- (2-(2- (2-chloro- 3'-(5-((S)-2- hydroxy- propyl)- 1- methyl- 4,5,6,7- tetrahydro- 1H- imidazo [4,5-c] pyridine-2- carbox- amido)-2'- methyl- biphenyl-3- ylcarba- moyl)-1- methyl-6,7- dihydro-1H- imidazo[4,5- c]pyridin- 5(4H)-

SMILES Cc1c(NC(=O)c2nc3c(n2C)CCN(C[C@H](C)O)C3)cccc1-c1cccc(NC(=O)c2nc3c(n2C)CCN(CC[C@H]2CC[C@H](C(=O)O)CC2)C3)c1Cl

InChI Key InChIKey=JGDDOFWORDELFS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468495   

LigandChemical structure of BindingDB Monomer ID 468495BDBM468495(trans-4- (2-(2- (2-chloro- 3'-(5-((S)-2- hydroxy- ...)
Affinity DataIC50: 0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
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Date in BDB:
6/11/2021
Entry Details
US Patent