BDBM468604 US10807944, Compound RLS3-5::US11731934, Compound RLS3-5

SMILES CCCCNNC(=O)c1cccc(I)c1

InChI Key InChIKey=BRRHPJMUCLJJGX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 468604   

TargetHistone deacetylase 1(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468604(US10807944, Compound RLS3-5 | US11731934, Compound...)
Affinity DataIC50: 3.14E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468604(US10807944, Compound RLS3-5 | US11731934, Compound...)
Affinity DataIC50: 3.14E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468604(US10807944, Compound RLS3-5 | US11731934, Compound...)
Affinity DataIC50: 4.70E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468604(US10807944, Compound RLS3-5 | US11731934, Compound...)
Affinity DataIC50: 4.70E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468604(US10807944, Compound RLS3-5 | US11731934, Compound...)
Affinity DataIC50: 5.00E+4nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
University of Florida Research Foundation

US Patent
LigandPNGBDBM468604(US10807944, Compound RLS3-5 | US11731934, Compound...)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2023
Entry Details
US Patent